Production of Hybrid-IgG/IgA Plantibodies with Neutralizing Activity against Shiga Toxin 1

Shiga toxin 1 (Stx1) is a virulence factor of enterohemorrhagic Escherichia coli, such as the O157:H7 strain. In the intestines, secretory IgA (SIgA) is a major component of the immune defense against pathogens and toxins. To form SIgA, the production of dimeric IgA that retains biological activity...

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Detalhes bibliográficos
Main Authors: Nakanishi, Katsuhiro, Narimatsu, Sanshiro, Ichikawa, Shiori, Tobisawa, Yuki, Kurohane, Kohta, Niwa, Yasuo, Kobayashi, Hirokazu, Imai, Yasuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842918/
https://ncbi.nlm.nih.gov/pubmed/24312238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080712
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