Detection of HIV-1 Neutralizing Antibodies in a Human CD4(+)/CXCR4(+)/CCR5(+) T-Lymphoblastoid Cell Assay System

Sensitive assays are needed to meaningfully assess low levels of neutralizing antibodies (NAbs) that may be important for protection against the acquisition of HIV-1 infection in vaccine recipients. The current assay of choice uses a non-lymphoid cell line (TZM-bl) that may lack sensitivity owing to...

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Autors principals: McLinden, Robert J., LaBranche, Celia C., Chenine, Agnès-Laurence, Polonis, Victoria R., Eller, Michael A., Wieczorek, Lindsay, Ochsenbauer, Christina, Kappes, John C., Perfetto, Stephen, Montefiori, David C., Michael, Nelson L., Kim, Jerome H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842913/
https://ncbi.nlm.nih.gov/pubmed/24312168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077756
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