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Release of initiation control by a mutational alteration in the R6K pi protein required for plasmid DNA replication.
Plasmid pRK419, a derivative of the naturally occurring antibiotic resistance plasmid R6K, contains the pir gene that codes for the pi initiation protein and the beta and gamma replication origins of R6K. A mutation in plasmid pRK419, designated cos405, results in an elevated plasmid copy number in...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1983
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384285/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6310578/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.18.5500 |
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