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MATE-CLEVER: Mendelian-inheritance-aware discovery and genotyping of midsize and long indels

Motivation: Accurately predicting and genotyping indels longer than 30 bp has remained a central challenge in next-generation sequencing (NGS) studies. While indels of up to 30 bp are reliably processed by standard read aligners and the Genome Analysis Toolkit (GATK), longer indels have still resist...

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Bibliographic Details
Main Authors: Marschall, Tobias, Hajirasouliha, Iman, Schönhuth, Alexander
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842759/
https://ncbi.nlm.nih.gov/pubmed/24072733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt556
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