Renoprotective capacities of non-erythropoietic EPO derivative, ARA290, following renal ischemia/reperfusion injury

BACKGROUND: ARA290 is a non-erythropoietic EPO derivative which only binds to the cytoprotective receptor complex (EPOR(2)-βcR(2)) consisting of two EPO-receptors (EPOR) and two β common receptors (βcR). ARA290 is renoprotective in renal ischemia/reperfusion (I/R). In a renal I/R model we focussed o...

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Main Authors: van Rijt, Willem G, Nieuwenhuijs-Moeke, Gertrude J, van Goor, Harry, Ottens, Petra J, Ploeg, Rutger J, Leuvenink, Henri GD
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842642/
https://ncbi.nlm.nih.gov/pubmed/24225194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-286
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