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Down Syndrome: From Understanding the Neurobiology to Therapy
Down syndrome (DS) is the most common example of a neurogenetic aneuploid disorder leading to mental retardation. In most cases, DS results from an extra copy of human chromosome 21 producing deregulated gene expression in brain that gives raise to subnormal intellectual functioning. Understanding t...
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Main Authors: | , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
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Society for Neuroscience
2010
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3842485/ https://ncbi.nlm.nih.gov/pubmed/21068296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3728-10.2010 |
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