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Down Syndrome: From Understanding the Neurobiology to Therapy

Down syndrome (DS) is the most common example of a neurogenetic aneuploid disorder leading to mental retardation. In most cases, DS results from an extra copy of human chromosome 21 producing deregulated gene expression in brain that gives raise to subnormal intellectual functioning. Understanding t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gardiner, Katheleen, Herault, Yann, Lott, Ira T., Antonarakis, Stylianos E., Reeves, Roger H., Dierssen, Mara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842485/
https://ncbi.nlm.nih.gov/pubmed/21068296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3728-10.2010
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