Prostaglandin E2-Induced Synaptic Plasticity in Neocortical Networks of Organotypic Slice Cultures

Traumatic brain injury (TBI) is a major cause of epilepsy, yet the mechanisms underlying the progression from TBI to epilepsy are unknown. TBI induces the expression of COX-2 (cyclooxygenase-2) and increases levels of prostaglandin E2 (PGE2). Here, we demonstrate that acutely applied PGE2 (2 μm) dec...

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Main Authors: Koch, Henner, Huh, Sung-Eun, Elsen, Frank P., Carroll, Michael S., Hodge, Rebecca D., Bedogni, Francesco, Turner, Michael S., Hevner, Robert F., Ramirez, Jan-Marino
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2010
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842478/
https://ncbi.nlm.nih.gov/pubmed/20810888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4665-09.2010
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