Murine Embryonic Stem Cell-Derived Pyramidal Neurons Integrate into the Cerebral Cortex and Appropriately Project Axons to Subcortical Targets

Although embryonic stem (ES) cells have been induced to differentiate into diverse neuronal cell types, the production of cortical projection neurons with the correct morphology and axonal connectivity has not been demonstrated. Here, we show that in vitro patterning is critical for generating neura...

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Hlavní autoři: Ideguchi, Makoto, Palmer, Theo D., Recht, Lawrence D., Weimann, James M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842463/
https://ncbi.nlm.nih.gov/pubmed/20089898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4318-09.2010
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