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Testing the Reproducibility of Multiple Displacement Amplification on Genomes of Clonal Endosymbiont Populations

The multiple displacement amplification method has revolutionized genomic studies of uncultured bacteria, where the extraction of pure DNA in sufficient quantity for next-generation sequencing is challenging. However, the method is problematic in that it amplifies the target DNA unevenly, induces th...

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Hlavní autoři: Ellegaard, Kirsten Maren, Klasson, Lisa, Andersson, Siv G. E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842359/
https://ncbi.nlm.nih.gov/pubmed/24312412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082319
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