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Functional Characteristics of the Naked Mole Rat μ-Opioid Receptor

While humans and most animals respond to µ-opioid receptor (MOR) agonists with analgesia and decreased aggression, in the naked mole rat (NMR) opioids induce hyperalgesia and severe aggression. Single nucleotide polymorphisms in the human mu-opioid receptor gene (OPRM1) can underlie altered behavior...

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Main Authors: Busch-Dienstfertig, Melanie, Roth, Clarisse A., Stein, Christoph
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842265/
https://ncbi.nlm.nih.gov/pubmed/24312175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079121
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