Effect of high-dose N-acetylcysteine on airway geometry, inflammation, and oxidative stress in COPD patients

BACKGROUND: Previous studies have demonstrated the potential beneficial effect of N-acetylcysteine (NAC) in chronic obstructive pulmonary disease (COPD). However, the required dose and responder phenotype remain unclear. The current study investigated the effect of high-dose NAC on airway geometry,...

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Main Authors: De Backer, Jan, Vos, Wim, Van Holsbeke, Cedric, Vinchurkar, Samir, Claes, Rita, Parizel, Paul M, De Backer, Wilfried
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2013
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842218/
https://ncbi.nlm.nih.gov/pubmed/24293993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S49307
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