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Quantification of shape and cell polarity reveals a novel mechanism underlying malformations resulting from related FGF mutations during facial morphogenesis

Fibroblast growth factor (FGF) signaling mutations are a frequent contributor to craniofacial malformations including midfacial anomalies and craniosynostosis. FGF signaling has been shown to control cellular mechanisms that contribute to facial morphogenesis and growth such as proliferation, surviv...

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Detalhes bibliográficos
Main Authors: Li, Xin, Young, Nathan M., Tropp, Stephen, Hu, Diane, Xu, Yanhua, Hallgrímsson, Benedikt, Marcucio, Ralph S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842176/
https://ncbi.nlm.nih.gov/pubmed/23906837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt369
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