Influence of Distal Resistance and Proximal Stiffness on Hemodynamics and RV Afterload in Progression and Treatments of Pulmonary Hypertension: A Computational Study with Validation Using Animal Models

We develop a simple computational model based on measurements from a hypoxic neonatal calf model of pulmonary hypertension (PH) to investigate the interplay between vascular and ventricular measures in the setting of progressive PH. Model parameters were obtained directly from in vivo and ex vivo me...

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Bibliographic Details
Main Authors: Su, Zhenbi, Tan, Wei, Shandas, Robin, Hunter, Kendall S.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842075/
https://ncbi.nlm.nih.gov/pubmed/24367392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/618326
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