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Granulocytes without degranulation: neutrophil function in granule-depleted cytoplasts.

Neutrophils respond to a variety of stimuli by generating superoxide anion, degranulating, and aggregating. Because it has been suggested that fusion of granules with the plasmalemma (degranulation) is necessary for aggregation and superoxide anion generation, we have tested whether these responses...

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Bibliographic Details
Main Authors: Korchak, H M, Roos, D, Giedd, K N, Wynkoop, E M, Vienne, K, Rutherford, L E, Buyon, J P, Rich, A M, Weissmann, G
Format: Artigo
Language:Inglês
Published: 1983
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC384169/
https://ncbi.nlm.nih.gov/pubmed/6308664
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