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Defective myoblasts identified in Duchenne muscular dystrophy.

A defect in the proliferative capacity of satellite cells, mononucleated precursors of mature muscle fibers, was found in clonal analyses of cells cultured from Duchenne muscular dystrophy (DMD) patients. The total yield of myoblasts per gram of muscle biopsy was decreased to 5% of normal. Of the DM...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Blau, H M, Webster, C, Pavlath, G K
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1983
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384144/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6576361/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.15.4856
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