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Detection of an altered heterochromatin structure in the absence of the nucleotide excision repair protein Rad4 in Saccharomyces cerevisiae

Rad4p is a DNA damage recognition protein essential for global genomic nucleotide excision repair in Saccharomyces cerevisiae. Here, we show that Rad4p binds to the heterochromatic HML locus. In a yeast mutant lacking Rad4p, an increased level of SIR complex binding at the HML locus is accompanied b...

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Autors principals: Zhang, Ling, Chen, Hua, Bi, Xin, Gong, Feng
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841322/
https://ncbi.nlm.nih.gov/pubmed/23839037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25457
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