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P2X7 receptor antagonism inhibits p38 MAPK activation and ameliorates neuronal apoptosis after subarachnoid hemorrhage in the rat

OBJECTIVE: Brilliant blue G (BBG), a selective P2X7 receptor (P2X7R) antagonist, exhibits neuroprotective properties. This study examined whether BBG treatment ameliorates early brain injury (EBI) after experimental subarachnoid hemorrhage (SAH), specifically via inhibiting p38 mitogen-activated pro...

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Bibliografiske detaljer
Main Authors: Chen, Sheng, Ma, Qingyi, Krafft, Paul R., Chen, Yujie., Tang, Jiping, Zhang, Jianmin, Zhang, John H.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841260/
https://ncbi.nlm.nih.gov/pubmed/23963136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31829a8246
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