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“Selective cell death mediated by small conditional RNAs” is not selective

Small conditional RNAs were used to kill cells selectively in a prior report. The method utilized the cellular innate immune response to dsRNA, causing PKR activation and cell death. We designed small conditional RNAs specific to a highly restricted transcript, that of the mesothelin gene expressed...

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Bibliografski detalji
Glavni autori: Patel, Kalpesh, Kern, Scott E
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841206/
https://ncbi.nlm.nih.gov/pubmed/23792574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.25093
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