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DOCK8 Interacts with Talin and WASPto Regulate Natural Killer Cell Cytotoxicity

Recently, patients with mutations in DOCK8 have been reported to have a combined immunodeficiency characterized by cutaneous viral infections and allergies. Natural killer (NK) cells represent a first-line defense against viral infections suggesting that DOCK8 might participate in NK cell function....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ham, Hyoungjun, Guerrier, Sabrice, Kim, JungJin, Schoon, Renee A., Anderson, Erik L., Hamann, Michael J., Lou, Zhenkun, Billadeau, Daniel D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841075/
https://ncbi.nlm.nih.gov/pubmed/23455509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202792
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