TRPV4 calcium entry and surface expression attenuated by inhibition of myosin light chain kinase in rat pulmonary microvascular endothelial cells

In previous studies, blockade or gene deletion of either myosin light chain kinase (MLCK) or the mechanogated transient receptor potential vanilloid 4 (TRPV4) channel attenuated mechanical lung injury. To determine their effects on calcium entry, rat pulmonary microvascular endothelial cells (RPMVEC...

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Detalhes bibliográficos
Main Authors: Parker, James C, Hashizumi, Masahiro, Kelly, Sarah V, Francis, Michael, Mouner, Marc, Meyer, Angela L, Townsley, Mary I, Wu, Songwei, Cioffi, Donna L, Taylor, Mark S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841052/
https://ncbi.nlm.nih.gov/pubmed/24303188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phy2.121
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