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Evolution of Energy Metabolism, Stem Cells and Cancer Stem Cells: How the Warburg and Barker Hypotheses Might Be Linked

The evolutionary transition from single cells to the metazoan forced the appearance of adult stem cells and a hypoxic niche, when oxygenation of the environment forced the appearance of oxidative phosphorylation from that of glycolysis. The prevailing paradigm in the cancer field is that cancers sta...

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Detalhes bibliográficos
Main Authors: Trosko, James E., Kang, Kyung-Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Stem Cell Research 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840988/
https://ncbi.nlm.nih.gov/pubmed/24298354
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