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Where is mTOR and what is it doing there?

Target of rapamycin (TOR) forms two conserved, structurally distinct kinase complexes termed TOR complex 1 (TORC1) and TORC2. Each complex phosphorylates a different set of substrates to regulate cell growth. In mammals, mTOR is stimulated by nutrients and growth factors and inhibited by stress to e...

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Bibliografische gegevens
Hoofdauteurs: Betz, Charles, Hall, Michael N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840941/
https://ncbi.nlm.nih.gov/pubmed/24385483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201306041
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