Efficient generation in vitro, from human peripheral blood cells, of monoclonal Epstein-Barr virus transformants producing specific antibody to a variety of antigens without prior deliberate immunization.

This paper describes a simple protocol for the efficient generation of large numbers of human monoclonal antibody-producing cells. This system is based on initial limiting-dilution culture after Epstein-Barr virus exposure of highly enriched precursors selected from peripheral blood mononuclear cell...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Winger, L, Winger, C, Shastry, P, Russell, A, Longenecker, M
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1983
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384063/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6308627/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.14.4484
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