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(Dichloromethylene)diphosphonate-induced impairment of T-lymphocyte function.

The daily subcutaneous administration of (dichloromethylene)diphosphonate (clodronate) to 3-day-old normal inbred Wistar-Furth rats for 30 days produces osteopetrotic bone lesions resembling those of the osteopetrotic mutants. Furthermore, tooth eruption is prevented, growth slows down, and signs of...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Milhaud, G, Labat, M L, Moricard, Y
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1983
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384060/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6224219/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.14.4469
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