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Autoimmune response directed against conserved determinants of nuclear envelope proteins in a patient with linear scleroderma.

We have studied the autoantibodies in the serum of a patient with linear scleroderma that specifically recognize the nuclear envelope of cultured cells. These antibodies bind to conserved determinants of nuclear lamins, the predominant mammalian nuclear envelope proteins. Of the three mammalian nucl...

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Autors principals: McKeon, F D, Tuffanelli, D L, Fukuyama, K, Kirschner, M W
Format: Artigo
Idioma:Inglês
Publicat: 1983
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC384040/
https://ncbi.nlm.nih.gov/pubmed/6192431
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