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Reduced tonic inhibition in striatal output neurons from Huntington mice due to loss of astrocytic GABA release through GAT-3

The extracellular concentration of the two main neurotransmitters glutamate and GABA is low but not negligible which enables a number of tonic actions. The effects of ambient GABA vary in a region-, cell-type, and age-dependent manner and can serve as indicators of disease-related alterations. Here...

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Main Authors: Wójtowicz, Anna M., Dvorzhak, Anton, Semtner, Marcus, Grantyn, Rosemarie
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840359/
https://ncbi.nlm.nih.gov/pubmed/24324407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncir.2013.00188
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