Knockdown of tyrosine hydroxylase in the nucleus of the solitary tract reduces elevated blood pressure during chronic intermittent hypoxia

Noradrenergic A2 neurons in nucleus tractus solitarius (NTS) respond to stressors such as hypoxia. We hypothesize that tyrosine hydroxylase (TH) knockdown in NTS reduces cardiovascular responses to chronic intermittent hypoxia (CIH), a model of the arterial hypoxemia observed during sleep apnea in h...

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Hlavní autoři: Bathina, Chandra Sekhar, Rajulapati, Anuradha, Franzke, Michelle, Yamamoto, Kenta, Cunningham, J. Thomas, Mifflin, Steve
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
Neural Control
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840319/
https://ncbi.nlm.nih.gov/pubmed/24049117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00260.2013
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