Knockdown of tyrosine hydroxylase in the nucleus of the solitary tract reduces elevated blood pressure during chronic intermittent hypoxia

Noradrenergic A2 neurons in nucleus tractus solitarius (NTS) respond to stressors such as hypoxia. We hypothesize that tyrosine hydroxylase (TH) knockdown in NTS reduces cardiovascular responses to chronic intermittent hypoxia (CIH), a model of the arterial hypoxemia observed during sleep apnea in h...

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Detalhes bibliográficos
Main Authors: Bathina, Chandra Sekhar, Rajulapati, Anuradha, Franzke, Michelle, Yamamoto, Kenta, Cunningham, J. Thomas, Mifflin, Steve
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Neural Control
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840319/
https://ncbi.nlm.nih.gov/pubmed/24049117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00260.2013
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