Central losartan attenuates increases in arterial pressure and expression of FosB/ΔFosB along the autonomic axis associated with chronic intermittent hypoxia

Chronic intermittent hypoxia (CIH) increases mean arterial pressure (MAP) and FosB/ΔFosB staining in central autonomic nuclei. To test the role of the brain renin-angiotensin system (RAS) in CIH hypertension, rats were implanted with intracerebroventricular (icv) cannulae delivering losartan (1 μg/h...

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Detalhes bibliográficos
Main Authors: Knight, W. David, Saxena, Ashwini, Shell, Brent, Nedungadi, T. Prashant, Mifflin, Steven W., Cunningham, J. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Neural Control
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840317/
https://ncbi.nlm.nih.gov/pubmed/24026072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00541.2012
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