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Thrombin selectively engages LIM kinase 1 and slingshot-1L phosphatase to regulate NF-κB activation and endothelial cell inflammation

Endothelial cell (EC) inflammation is a central event in the pathogenesis of many pulmonary diseases such as acute lung injury and its more severe form acute respiratory distress syndrome. Alterations in actin cytoskeleton are shown to be crucial for NF-κB regulation and EC inflammation. Previously,...

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Autori principali: Leonard, Antony, Marando, Catherine, Rahman, Arshad, Fazal, Fabeha
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840277/
https://ncbi.nlm.nih.gov/pubmed/24039253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00071.2013
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