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Thrombin selectively engages LIM kinase 1 and slingshot-1L phosphatase to regulate NF-κB activation and endothelial cell inflammation

Endothelial cell (EC) inflammation is a central event in the pathogenesis of many pulmonary diseases such as acute lung injury and its more severe form acute respiratory distress syndrome. Alterations in actin cytoskeleton are shown to be crucial for NF-κB regulation and EC inflammation. Previously,...

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Bibliografiska uppgifter
Huvudupphovsmän: Leonard, Antony, Marando, Catherine, Rahman, Arshad, Fazal, Fabeha
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840277/
https://ncbi.nlm.nih.gov/pubmed/24039253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00071.2013
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