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Fluid reabsorption in proximal convoluted tubules of mice with gene deletions of claudin-2 and/or aquaporin1

Deletions of claudin-2 (Cldn2) and aquaporin1 (AQP1) reduce proximal fluid reabsorption (PFR) by about 30% and 50%, respectively. Experiments were done to replicate these observations and to determine in AQP1/claudin-2 double knockout mice (DKO) if the effects of deletions of these established water...

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Detalhes bibliográficos
Main Authors: Schnermann, Jurgen, Huang, Yuning, Mizel, Diane
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840226/
https://ncbi.nlm.nih.gov/pubmed/24049145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00342.2013
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