Defective prolactin signaling impairs pancreatic β-cell development during the perinatal period

Prolactin (PRL) and placental lactogens stimulate β-cell replication and insulin production in pancreatic islets and insulinoma cells through binding to the PRL receptor (PRLR). However, the contribution of PRLR signaling to β-cell ontogeny and function in perinatal life and the effects of the lacto...

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Main Authors: Auffret, Julien, Freemark, Michael, Carré, Nadège, Mathieu, Yves, Tourrel-Cuzin, Cécile, Lombès, Marc, Movassat, Jamileh, Binart, Nadine
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840213/
https://ncbi.nlm.nih.gov/pubmed/24064341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00636.2012
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