Pertussis toxin substrate, the putative Ni component of adenylyl cyclases, is an alpha beta heterodimer regulated by guanine nucleotide and magnesium.

The final step in a scheme for the purification of the guanine nucleotide- and Mg2+-binding stimulatory regulatory component (Ns) of adenylyl cyclase [adenylate cyclase; ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] from human erythrocyte membranes involves chromatography over hydroxylapatite (HA...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Codina, J, Hildebrandt, J, Iyengar, R, Birnbaumer, L, Sekura, R D, Manclark, C R
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1983
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384020/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6308612/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.14.4276
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