Differential Effect of Soy Isoflavones in Enhancing High Intensity Radiotherapy and Protecting Lung Tissue in a Pre-Clinical Model of Lung Carcinoma

BACKGROUND: Radiotherapy of locally-advanced non-small cell lung cancer is limited by radiation-induced pneumonitis and fibrosis. We have further investigated the role of soy isoflavones to improve the effect of a high intensity radiation and reduce lung damage in a pre-clinical lung tumor model. ME...

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Main Authors: Hillman, Gilda G., Singh-Gupta, Vinita, Hoogstra, David J., Abernathy, Lisa, Rakowski, Joseph, Yunker, Christopher K., Rothstein, Shoshana E., Sarkar, Fazlul H., Gadgeel, Shirish, Konski, Andre A., Lonardo, Fulvio, Joiner, Michael C.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840154/
https://ncbi.nlm.nih.gov/pubmed/24021346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.radonc.2013.08.015
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