Disruption of Dopamine Neuron Activity Pattern Regulation through Selective Expression of a Human KCNN3 Mutation

The calcium-activated small conductance potassium channel, SK3, plays an essential role in the regulation of dopamine neuron activity patterns. Here we demonstrate that expression of a human disease-related SK3 mutation (hSK3Δ) in dopamine neurons of mice disrupts the balance between tonic and phasi...

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Hlavní autoři: Soden, Marta E., Jones, Graham L., Sanford, Christina A., Chung, Amanda S., Güler, Ali D., Chavkin, Charles, Luján, Rafael, Zweifel, Larry S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840077/
https://ncbi.nlm.nih.gov/pubmed/24206670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.07.044
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