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Structural Analysis of microRNA-Target Interaction by Sequential Seed Mutagenesis and Stem-Loop 3' RACE

BACKGROUND: As a consequence of recent RNAseq efforts, miRNAomes of diverse tissues and species are available. However, most interactions between microRNAs and regulated mRNAs are still to be deciphered. While in silico analysis of microRNAs results in prediction of hundreds of potential targets, bo...

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Detalhes bibliográficos
Main Authors: Bohmer, Marc, Sharbati, Jutta, zur Bruegge, Jennifer, Einspanier, Ralf, Sharbati, Soroush
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839922/
https://ncbi.nlm.nih.gov/pubmed/24282594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081427
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