Targeted delivery of let-7a microRNA encapsulated ephrin-A1 conjugated liposomal nanoparticles inhibit tumor growth in lung cancer

MicroRNAs (miRs) are small noncoding RNA sequences that negatively regulate the expression of target genes by posttranscriptional repression. miRs are dysregulated in various diseases, including cancer. let-7a miR, an antioncogenic miR, is downregulated in lung cancers. Our earlier studies demonstra...

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Detalhes bibliográficos
Main Authors: Lee, Hung-Yen, Mohammed, Kamal A, Kaye, Fredric, Sharma, Parvesh, Moudgil, Brij M, Clapp, William L, Nasreen, Najmunnisa
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839802/
https://ncbi.nlm.nih.gov/pubmed/24293999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S41782
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