c-myc activation renders proliferation of Epstein-Barr virus (EBV)-transformed cells independent of EBV nuclear antigen 2 and latent membrane protein 1.

Two genetic events contribute to the development of endemic Burkitt lymphoma (BL) infection of B lymphocytes with Epstein-Barr virus (EBV) and the activation of the protooncogene c-myc through chromosomal translocation. The viral genes EBV nuclear antigen 2 (EBNA2) and latent membrane protein 1 (LMP...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Polack, A, Hörtnagel, K, Pajic, A, Christoph, B, Baier, B, Falk, M, Mautner, J, Geltinger, C, Bornkamm, G W, Kempkes, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38398/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8816814/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.19.10411
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