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Structural basis of ATG3 recognition by the autophagic ubiquitin-like protein ATG12

The autophagic ubiquitin-like protein (ublp) autophagy-related (ATG)12 is a component of the ATG12∼ATG5–ATG16L1 E3 complex that promotes lipid conjugation of members of the LC3 ublp family. A role of ATG12 in the E3 complex is to recruit the E2 enzyme ATG3. Here we report the identification of the A...

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Autors principals: Metlagel, Zoltan, Otomo, Chinatsu, Takaesu, Giichi, Otomo, Takanori
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839761/
https://ncbi.nlm.nih.gov/pubmed/24191030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314755110
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