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Reduced IGF signaling prevents muscle cell death in a Caenorhabditis elegans model of muscular dystrophy
Duchenne muscular dystrophy, a fatal degenerative muscle disease, is caused by mutations in the dystrophin gene. Loss of dystrophin in the muscle cell membrane causes muscle fiber necrosis. Previously, loss-of-function mutations in dys-1, the Caenorhabditis elegans dystrophin ortholog, were shown to...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839758/ https://ncbi.nlm.nih.gov/pubmed/24191049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308866110 |
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