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Distinct H-2-linked Ir genes control both antibody and T cell responses to different determinants on the same antigen, myoglobin

The murine antibody and T lymphocyte proliferative responses to sperm whale myoglobin (Mb) were found to be under control of two distinct H-2-linked immune response (Ir) genes (Ir-Mb-1, mapping in the I-A subregion, and Ir-Mb-2, mapping in I-C). H-2(d) mice (B10.D2 and DBA/2), with both genes, were...

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Detalhes bibliográficos
Main Authors: Berzofsky, Jay A., Richman, Lee K., Killion, Douglas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC383974/
https://ncbi.nlm.nih.gov/pubmed/91172
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