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Regulation of glutamate receptor internalization by the spine cytoskeleton is mediated by its PKA-dependent association with CPG2

A key neuronal mechanism for adjusting excitatory synaptic strength is clathrin-mediated endocytosis of postsynaptic glutamate receptors (GluRs). The actin cytoskeleton is critical for clathrin-mediated endocytosis, yet we lack a mechanistic understanding of its interaction with the endocytic proces...

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Autors principals: Loebrich, Sven, Djukic, Biljana, Tong, Zachary J., Cottrell, Jeffrey R., Turrigiano, Gina G., Nedivi, Elly
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839735/
https://ncbi.nlm.nih.gov/pubmed/24191017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318860110
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