Rescue of a primary myelofibrosis model by retinoid-antagonist therapy

Molecular targeting of the two receptor interaction domains of the epigenetic repressor silencing mediator of retinoid and thyroid hormone receptors (SMRT(mRID)) produced a transplantable skeletal syndrome that reduced radial bone growth, increased numbers of bone-resorbing periosteal osteoclasts, a...

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Main Authors: Hong, Suk-Hyun, Dvorak-Ewell, Melita, Stevens, Hazel Y., Barish, Grant D., Castro, Glenda L., Nofsinger, Russell, Frangos, John A., Shoback, Dolores, Evans, Ronald M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2013
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839709/
https://ncbi.nlm.nih.gov/pubmed/24191050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318974110
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