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CNTF-mediated protection of photoreceptors requires initial activation of the cytokine receptor gp130 in Müller glial cells
Ciliary neurotrophic factor (CNTF) acts as a potent neuroprotective agent in multiple retinal degeneration animal models. Recently, CNTF has been evaluated in clinical trials for the inherited degenerative disease retinitis pigmentosa (RP) and for dry age-related macular degeneration (AMD). Despite...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839707/ https://ncbi.nlm.nih.gov/pubmed/24191003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303604110 |
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