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Immunochemical characterization of synthetic hexa-, octa- and decasaccharide conjugate vaccines for Vibrio cholerae O:1 Serotype Ogawa with emphasis on antigenic density and chain length

Cholera remains to be a global health problem without suitable vaccines for endemic control or outbreak relief. Here we describe a new parenteral vaccine based on neoglyco-conjugate of synthetic fragments of O-specific polysaccharide (O-SP) of Vibrio cholerae O1, serotype Ogawa. Hexa-, octa- and dec...

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Autori principali: Ftacek, Peter, Nelson, Victor, Szu, Shousun C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839634/
https://ncbi.nlm.nih.gov/pubmed/23955520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10719-013-9491-9
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