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Smac-Mimetic–Induced Epithelial Cell Death Reduces the Growth of Renal Cysts

Past efforts to pharmacologically disrupt the development and growth of renal cystic lesions focused primarily on normalizing the activity of a specific signaling molecule, but the effects of stimulating apoptosis in the proliferating epithelial cells have not been well studied. Although benign, ADP...

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Detalhes bibliográficos
Main Authors: Fan, Lucy X., Zhou, Xia, Sweeney, William E., Wallace, Darren P., Avner, Ellis D., Grantham, Jared J., Li, Xiaogang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839552/
https://ncbi.nlm.nih.gov/pubmed/23990677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013020176
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