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Small molecule antagonists of melanopsin-mediated phototransduction
Melanopsin, expressed in a subset of retinal ganglion cells, mediates behavioral adaptation to ambient light and other non-image forming photic responses. This has raised the possibility that pharmacological manipulation of melanopsin can modulate several CNS responses including photophobia, sleep,...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839535/ https://ncbi.nlm.nih.gov/pubmed/23974117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1333 |
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