Small molecule antagonists of melanopsin-mediated phototransduction

Melanopsin, expressed in a subset of retinal ganglion cells, mediates behavioral adaptation to ambient light and other non-image forming photic responses. This has raised the possibility that pharmacological manipulation of melanopsin can modulate several CNS responses including photophobia, sleep,...

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Main Authors: Jones, Kenneth A., Hatori, Megumi, Mure, Ludovic S., Bramley, Jayne R., Artymyshyn, Roman, Hong, Sang-Phyo, Marzabadi, Mohammad, Zhong, Huailing, Sprouse, Jeffrey, Zhu, Quansheng, Hartwick, Andrew T.E., Sollars, Patricia J., Pickard, Gary E., Panda, Satchidananda
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839535/
https://ncbi.nlm.nih.gov/pubmed/23974117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1333
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