Massively parallel resequencing of the isogenic Drosophila melanogaster strain w(1118); iso-2; iso-3 identifies hotspots for mutations in sensory perception genes

We used the Illumina reversible-short sequencing technology to obtain 17-fold average depth (s.d. ~8) of ~94% of the euchromatic genome and ~1–5% of the heterochromatin sequence of the Drosophila melanogaster isogenic strain w(1118); iso-2; iso-3. We show that this strain has a ~9 kb deletion that u...

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Main Authors: Platts, Adrian E., Land, Susan J., Chen, Lang, Page, Grier P., Rasouli, Parsa, Wang, Luan, Lu, Xiangyi, Ruden, Douglas M.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839425/
https://ncbi.nlm.nih.gov/pubmed/19690466
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