Heavy chain of HLA-A and HLA-B antigens is conformationally labile: a possible role for beta 2-microglobulin.

The three-dimensional organization of HLA antigens has been investigated by spectroscopic and immunochemical techniques. Measurement of the circular dichroism shows that in papain-solubilized HLA the heavy chain as well as the previously studied light chain (beta 2-microglobulin) consists predominan...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Lancet, D, Parham, P, Strominger, J L
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1979
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383931/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/91170/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.8.3844
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