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Immunotitration of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in various physiological states.

The immunotitration of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase [mevalonate:NADP+ oxidoreductase [CoA-acylating), EC 1.1.1.34], the major regulatory enzyme in cholesterol biosynthesis, by HMG-CoA reductase antiserum is described. This technique provides the advantage that one can ra...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Hardgrave, J E, Heller, R A, Herrera, M G, Scallen, T J
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1979
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383929/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/386352/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.8.3834
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